Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use

Extraction of potential adverse drug events from medical case reports

: The sheer amount of information about potential adverse drug events published in medical case reports pose major challenges for drug safety experts to perform timely monitoring. Efficient strategies for identification and extraction of information about potential adverse drug events from free-text resources are needed to support pharmacovigilance research and pharmaceutical decision making. T...

Reducing Adverse Events and Hospitalizations Associated with Drug Interactions

A drug-drug interaction is a pharmacokinetic or pharmacodynamic influence of one drug on another, which can reduce the effectiveness of one or both of the interacting drugs or can lead to toxic effects.1 It is estimated that such drug interactions cause up to 2.8% of hospital admissions,2 and they can lead to serious adverse outcomes for patients. One drug combination that has resulted in death...

Cannabidiol as potential anticancer drug.

Over the past years, several lines of evidence support an antitumourigenic effect of cannabinoids including Δ(9)-tetrahydrocannabinol (Δ(9)-THC), synthetic agonists, endocannabinoids and endocannabinoid transport or degradation inhibitors. Indeed, cannabinoids possess anti-proliferative and pro-apoptotic effects and they are known to interfere with tumour neovascularization, cancer cell migrati...

Adverse drug events Hospitalwide adverse drug events before and after limiting weekly work hours of medical residents to 80

Purpose. Adverse drug events (ADEs) at a hospital before and after the weekly work hours of medical residents were limited to 80 were studied. Methods. The study population included all adults admitted to a 750-bed academic tertiary care hospital where resident physicians provide direct care under the supervision of faculty attending physicians. The six-month period after implementation of the ...

ADVERSE EVENTS Surveillance Systems for Adverse Events and Medical Errors